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But, but but...We ArE all the SAME! Differences are simply "skin deep"....

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  • But, but but...We ArE all the SAME! Differences are simply "skin deep"....

    http://medicalxpress.com/news/2014-0...es-factor.html

    Researchers have identified the first genetic variations linked to race that begin to explain a higher risk of death among some African American and Caucasian patients taking the anti-clotting drug clopidogrel (Plavix) after a heart attack.

    These variants increased patients' risk of dying in the year following a first heart attack, but they appeared to do so for different reasons depending on race, according to a study at Washington University School of Medicine in St. Louis.

    In particular, the team found that two DNA variants common in African Americans were associated with an increased risk of both bleeding and death. In Caucasians, a different variant was linked to additional heart attacks and a higher risk of death.

    The research is published June 17 in the American Heart Association journal Circulation: Cardiovascular Genetics.

    The variations influence the way people metabolize clopidogrel and can alter its effectiveness. The blood-thinning drug commonly is prescribed after a heart attack to reduce the likelihood of another heart attack or a stroke.

    "The research is provocative," said the study's first author, cardiologist Sharon Cresci, MD, assistant professor of medicine and of genetics. "Knowing about potential genetic differences based on race can help physicians tailor drugs to patients based on their genetic makeup."

    Clopidogrel is metabolized in the liver, where it is turned into its active form via a group of enzymes called cytochrome P450, or CYP for short. Although clopidogrel is effective in many patients, earlier studies determined that some people metabolize the drug better than others.

    Indeed, in 2010, the Food and Drug Administration added a "black box" warning to labels of clopidogrel after research that primarily involved Caucasians showed that people with a particular CYP genetic variant metabolized the drug poorly, which reduced the amount of the drug circulating in the blood. These patients had a higher risk of heart attack and stroke.

    Additional studies showed that other CYP gene variants are linked to the rapid metabolism of clopidogrel and that patients with those variants had a higher risk of bleeding.

    But it has not been clear until now that the effects of these particular gene variations can vary by race in patients taking clopidogrel after a heart attack.

    For the study, the researchers analyzed CYP variants among 2,062 Caucasians and 670 African Americans who suffered heart attacks. Nearly 80 percent of the Caucasians and 65 percent of the African Americans were prescribed clopidogrel. The patients were enrolled in a major study known as TRIUMPH (Translational Research Investigating Underlying disparities in acute Myocardial infarction Patients' Health) conducted from 2005 to 2008 at 24 U.S. hospitals, including Barnes-Jewish Hospital in St. Louis.

    Among patients taking clopidogrel, the one-year mortality rate for African Americans was 7.2 percent, compared with 3.6 percent for Caucasians.

    Caucasians who carried the CYP2C19*2 variant, which has been linked to poor metabolism of the drug, had a higher rate of repeat heart attacks and death. The higher rate of heart attacks is consistent with the slower metabolism of clopidogrel.

    However, among African Americans treated with clopidogrel, the CYP2C19*2 variant was not associated with a higher rate of death.

    Rather, African Americans had higher rates of bleeding and death if they carried either of two other variants: CYP1A2*1C or CYP2C19*17, the latter of which has been associated with the rapid metabolism of clopidogrel. Among Caucasians on clopidogrel, neither variant increased the risk of death

  • #2
    Seriously? Who cares.

    I've seen a lot of your stuff on here, and it reeks of racism. Yes, people have minor differences. No big deal.

    You believe in god right? Does 'All men are created equal' mean anything to you? Does it mean were the same? No. However, if you believe in god, we are all created equally.

    Attempting to highlight minor differences between races is not going to get you, or anybody else, anywhere.

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    • #3
      Men and women aren't the same, but we are equal.

      What's next, more threads depicting the major differences between men and women?

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      • #4
        A two-liter bottle of Diet Coke just after Mentos were dropped into it

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        • #5
          Originally posted by pricejj View Post
          Seriously? Who cares.

          I've seen a lot of your stuff on here, and it reeks of racism. Yes, people have minor differences. No big deal.

          You believe in god right? Does 'All men are created equal' mean anything to you? Does it mean were the same? No. However, if you believe in god, we are all created equally.

          Attempting to highlight minor differences between races is not going to get you, or anybody else, anywhere.

          Equality of opportunity isn't the same as equality of OUTCOMES. When you hear this current governing party talk about disparate impact and incarceration rate disparities,wealth disparities etc, they aren't speaking to equality of opportunity. They are speaking to equality of outcomes. And for the same reason that our favorite football team is 78% black, our wealth disparity in this country also is unequal. You're simply naive to not address the obvious that plays out everyday.

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          • #6
            txtebow logic:

            Black people metabolize a man-made synthetic differently, therefore more black people are poor.

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            • #7
              Originally posted by txtebow View Post
              Equality of opportunity isn't the same as equality of OUTCOMES. When you hear this current governing party talk about disparate impact and incarceration rate disparities,wealth disparities etc, they aren't speaking to equality of opportunity. They are speaking to equality of outcomes. And for the same reason that our favorite football team is 78% black, our wealth disparity in this country also is unequal. You're simply naive to not address the obvious that plays out everyday.
              Wealth disparity has nothing to do with the fact that all people are created equal. Like I said already, if you believe in god, or the US Constitution you would already know that.

              Just because the current administration race baits doesn't make it right. Don't fall into their trap. They want people to be divided. It makes us easy to conquer. That's how special interests get them elected.

              Wage equality is a complete joke. Different jobs require different skills. Some skills are worth more on the free market than others. That doesn't have anything to do with equal rights.


              Like Bernie Mac said, 'Black people and white people are the same, but we're different".
              Last edited by pricejj; 06-19-2014, 09:12 PM.

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              • #8
                wow....welcome to my ignore list

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                • #9
                  This just in: black people have genes that cause their skin to be darker, hence they are all uppity.

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                  • #10
                    Originally posted by txtebow View Post
                    And for the same reason that our favorite football team is 78% black, our wealth disparity in this country also is unequal.
                    And for the same reason that our wealth disparity is unequal, our beverage differences are also inconsistent in their similarities.

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                    • #11
                      Originally posted by Arkie View Post
                      And for the same reason that our wealth disparity is unequal, our beverage differences are also inconsistent in their similarities.

                      For the same reason why all dogs are considered Canines, yet some are considered DANGEROUS and not allowed within certain municipalities.

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                      • #12
                        Originally posted by bowtown View Post
                        txtebow logic:

                        Black people metabolize a man-made synthetic differently, therefore more black people are poor.

                        For largely the same reason that these GENETICS play a role in the ABILITY OF SOME TO METABOLIZE A MEDICATION INTO AN ACTIVE OR INACTIVE METABOLITE, (or to run fast, or jump high) GENETICS also play a role in the ability to function within our WESTERN society ---and as evidenced by criminality, educational scores, joblessness etc. some peoples GENETICS are better than others at THAT as well. You naïve twit.

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                        • #13


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                          • #14
                            Originally posted by DenverBrit View Post


                            Morgan freeman is correct.

                            http://breakingbrown.com/2014/06/mor...me-inequality/

                            "“Why would race have anything to do with it?” he continued, “Put your mind to what you want to do and go for that. It’s kind of like religion to me, it’s a good excuse for not getting there.”

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                            • #15
                              Originally posted by DenverBrit View Post


                              I'm not expressing "racism"..I'm expressing facts of SCIENCE.

                              You ****ing C O W A R D

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