Obviously, things could change as players move up and down the board, but based on current projections:
1) Matt Elam, S, Florida - Makes tons on plays, is great in coverage and physical down in the box. Reminds me of Bob Sanders.
2) DeAndre Hopkins, Wr, Clemson - Homer pick, but I think he'll be a playmaker right off the bat in the slot.
3) Jonathan Cooper, G/C, North Carolina - Versatile interior lineman who can play any of the three inside spots. Extremely athletic. I like him because it provides depth and competition across the interior. Not chained to one spot.
I don't expect a MLB with 1st round value to be available. DT typically has a low first year impact, so with the "Manning window" I don't expect that to be the pick.