Interesting the debate. I think Biden went overkill with the smiling and laughing. He should have reigned it in a bit, especially on the sensitive issues. Biden had better responses on foreign policy and Medicare, which I expected. I thin Ryan pretty much destroyed the idea that the Rich "can pay for evrerything" as a general philosophy and again, predictably had better answers on economic issues.
Biden did a much better job selling his message to America and was better able to keep his views simplified. I think the smirking/laughing was too much and at times he became too aggressive.
Ryan was able to stay calm and stuck to his answers but got lost in the intricacies and by allowing Biden and the moderator to push him around, I think he can across as "just some guy." It's strange that Sarah Palin did better against Biden than Ryan did.
I would give the debate to Biden, but I am curious to see the fallout. Biden came at Ryan like the left wants to see conservatives attacked: Disrespectful, dismissive, sarcastic, and at times outright hostile. This may have been a "let's excite the voter base" play. I think his appeal to the middle class was good, but I think he may have come across as too hostile and at times pretty arrogant. He interrupted the moderator and Ryan several times and acted like he couldn't take anything that was being brought up as even remotely credible. The internet is already latching on to "the smirk" so it's going to be an issue. This is what I thought they might do and if all they wanted was to was energize the base, then that's fine. However if it plays like it's starting to: too much, too arrogant, too disrespectful, it may not pan out with the middle voters as much.
For Ryan, he needs more experience. Biden beat on some issues, and on other issues where Ryan was more substantive and supported by facts, Biden did a better job of re-framing the argument around parameters people can identify with or just shifting the argument all together. Ryan needs to realize who he's really talking to. Hint: It wasn't the moderator.
At the end of the day I don't believe VP debates make too much of a difference. Ultimately this is a fight between Romney and Ryan.