When looking at poly-framed semiautos or "Airweight" revolvers, remember that a light gun is easy to carry, but harder to shoot. The reduced weight of the gun increases the felt recoil and makes followup shots less accurate.
If you are looking for a non-carry pistol, I would recommend a non-poly full size pistol like a Beretta 92FS, Sig P226, or a full size revolver. I prefer 9MM because of the reduced recoil, reduced muzzle flash, and higher ammo capacity, but there are arguments to be made for other rounds as well (i.e. .40, .357Sig, .45).
For carry, you should definitely try before you buy if you can. The S&W "Airweight" revolvers are particularly annoying to shoot.