Check out Washington Park. It's close to where you are staying. You can take a walk around the park and check out the cool houses. This place will be busy on Friday PM, all day Sat. weather permitting.
Great dining all around Cherry Creek. For a good burger go to the Cherry Cricket in Cherry Creek North (I think it's at 2nd and just east of University) For some great Italian Food try Carmine's on Penn. Locally owned family style Italian place. Reservations recommended. Gov'nrs Park is a great bar with a great happy hour (4-7 everyday) A good Asian Restaurant in Cheery Creek is Little Ollie's.
The new art Museum just opened up downtown. I've heard good things so far.
What kind of stuff are you all looking to do Rascal (Hike, bike ride, etc)?