View Full Version : Albert Hofmann dies at age 102
05-01-2008, 09:21 AM
Albert Hofmann dies at age 102 (http://www.technoccult.com/archives/2008/04/29/lsd-inventor-albert-hofmann-dies-at-age-102/)
05-01-2008, 10:06 AM
05-01-2008, 10:17 AM
Where's Timothy Leary when you need him?
05-01-2008, 11:40 AM
Is the Mane crawling to a halt for anyone else lately?
05-01-2008, 12:03 PM
The world thanks you sir.
05-01-2008, 12:48 PM
It was first published that the double helix is the structure of DNA by James D. Watson and Francis Crick in 1953, based on work by Rosalind Franklin. The double helix shape is very strong. DNA takes this shape over a straight shape naturally for two reasons. It must be 'double' so it can reproduce itself and the helix, being intertwined, is stronger than two parallel chains because pulling it in any one direction won't break it apart.
05-01-2008, 02:21 PM
RIP. Crazy bastard. Did a lethal hit of LSD his first time doing it, tripped balls and rode his bike. Awesome.
05-01-2008, 02:38 PM
I stumbled upon a message board post by another guy made famous by lsd: Owsley Stanley.
<TABLE class=tborder id=post5966373 cellSpacing=1 cellPadding=6 width="100%" align=center border=0><TBODY><TR><TD class=thead>23:14 <!-- / status icon and date -->
</TD><TD width="100%"> </TD><TD vAlign=top noWrap width=170>Plan: zero-carb
Stats: 140/140/140 http://forum.lowcarber.org/images/male.gif
</TD></TR></TBODY></TABLE><!-- / user info --></TD></TR><TR><TD class=alt1><!-- message, attachments, sig --><!-- icon and title -->http://forum.lowcarber.org/images/icons/icon1.gif The real human diet is a totally carnivorous one.
<HR style="COLOR: #ffcc99" SIZE=1><!-- / icon and title --><!-- message -->Hello all,
I have been eating the natural human dietary regime for over 47 years now. I do not eat anything whatsoever from vegetable sources. The only things veggie I use are spices. My diet is usually 60% fat and 40% protein by calories. I used to eat 80/20 when younger and about twice as much quantity of meat also, but that seems too much energy at my age, which is 71- even though I am very active. I think the body actually becomes more efficient with energy as you age, but I have no way of proving it true. Otherwise, my body today is very like it was at the age of 30. I figure most of what we call 'aging' is due to insulin damage to the collagen and other body structures. No carbs = no insulin. I don't heal quite as fast when injured as I did as a youngster, however. But I have few wrinkles, and my skin is still strong and elastic.
At this point I would like to point out that a zero carb diet does NOT cause ketosis. The body rapidly adapts within a few weeks and begins consuming the ketones from fat metabolism. A fully keto-adapted body excretes no ketones in the urine. A metabolic by product, 'ketone bodies' are actually a special kind of carb, and they substitute for glucose at the structures which use it. They have the added advantage of making you feel good- and well fed.
The body cannot store dietary fat, there is no mechanism for transport across the adipose cell's wall, nor can it 'burn' carbs, which actually are toxic in more than the tiny amount required by the brain and a few other structures. The body converts dietary carbs (all convert to glucose as they are absorbed) into body fat. The conversion mechanism requires insulin which is very tissue-damaging. It is correct to say that dietary carbs are the base cause of both heart blockage and diabetes, (not a disease).
I must warn all of you that it is very unlikely that very many will be able to eat as I do over the long term, or in fact, to follow any diet for long which is much different from the one you were trained to as a baby/child. This is because diet is learned much the same way language, dress and behaviour is, and is buried deep and inaccessible, a part of your acculturation/socialisation. The very thing which makes us human is that deep and almost instinctive complex of behaviour.
It requires a powerful will and a determination to change, in order to succeed in adopting the 'extreme' diet which this website is based on. Even those who are morbidly obese, as powerful a motivation as any I can imagine will have 'cravings' for what I call 'non-food' (all vegetation and carbs) which will eventually prove irresistible. A few may manage to stay on the diet for years, but unless you are prepared to stick with it for maybe ten or more years, you will drift back into eating what I consider poison. For some reason my mum was not interested in forcing me to eat the veggies I hated so, and i was able to eat only what I liked- mostly meat, especially hamburger and the fat those at our table would cut from their steaks. Still I had massive struggles abandoning the 'civilised diet'.
I suggest that no non-food be taken home, none allowed in your fridge or pantry (out of sight is hopefully out of mind). Make a request when seated in a restaurant that the bread bin be removed (but please leave the butter), and when ordering, request that the vegetables be removed from the plate in the kitchen (just say you don't like to see 'good food go to waste').
Even during the years I was soundman for Grateful Dead, I stuck to my guns and remained totally carnivorous. I am restricted by the forums rules (as I read them) from telling about my essay on diet and exercise which is posted on my website. Basically it states that humans were totally hunting peoples until the end of the paleolithic age. No paleolithic archeological dig has ever produced any food residues from vegetables. Chemical analysis of bones from the digs indicates they are the same composition as the African lion- thus, virtually no intake of vegetation. There were no 'hunter-gatherer' societies until the neolithic, even though some modern HG tribes still made and used typical paleolithic napped-stone tools. The so called Nearthin and Paleodiet thus are both nonsense, true paleolithic people were total carnivores and ate no veggies whatsoever.
In the relatively short evolutionary period since the consumption of vegetables as food there has not been any real adaptation to such low grade low energy, difficult to digest foods. Because we have no adaptation to digesting or processing vegetables as food, they are all basically very bad for us.
We evolved as an active, group-hunting animal. We have a high natural requirement for physical exercise and cannot live long or be healthy without a lot of it.
I hope my post is of some help to others. Just persist. I show that it IS possible to overcome your dietary socialisation.
05-02-2008, 03:44 PM
How Do Hallucinogens Work?
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Swiss chemist Albert Hofmann, who discovered the hallucinogenic drug LSD, died yesterday. But the LSD trip is far from over as scientists bring lucidity to how hallucinogens work.
Also called psychedelics, hallucinogens alter a person's perception, mood and a slew of other mental processes. Hallucinogen history goes back centuries as people worldwide have taken the drugs to induce altered states for religious and spiritual purposes.
While LSD (lysergic acid diethylamide), mescaline and other psychedelics were studied in the past, research largely came to a halt after recreational abuse of the drugs in the 1960s, with some work resuming in the 1990s. Many studies now rely on animal models such as mice.
One human study published in the journal Psychopharmacology revealed the active ingredient in hippie mushrooms, called psilocybin, elicited "mystical experiences" for participants that reportedly led to behavior changes lasting for weeks. However, nearly one-third of the participants had a bad trip, reporting that they found the drug experience frightening.
Research has suggested hallucinogens primarily do their magic in the brain's cortex, where the drugs activate specific receptors called 5-HT2A receptors (2ARs) that are normally triggered by serotonin.
"In order to function, [the cortex is] integrating different signals, for example glutamate signals and serotonin signals," said neuroscientist Stuart Sealfon of Mount Sinai School of Medicine in New York, "and what hallucinogens must be doing is they are disrupting this process so that sensory perception is altered by them."
However, not all compounds that activate these receptors lead to mind-bending trips. "What was it that made hallucinogens have their unique properties?" Sealfon said.
Scientists once thought of receptors in terms of "locks and keys," in which certain drugs fit into a specific receptor as a key fits into a lock. That receptor would then turn on and signal to other molecules in the cell.
But that's not the case for hallucinogens. Research by Sealfon and his colleagues published last year in the journal Neuron revealed the serotonin-2A receptor has more than one "on" position.
"When a non-hallucinogen activates the receptor, it causes one pattern of signaling of the cells in the brain that is not hallucinogenic," Sealfon told LiveScience. "When a hallucinogen turns on this receptor, the receptor we infer must go into a different position and that leads to a different pattern in responses in the cell and is what makes the hallucinogen have its unique effect."
Brains are mysterious, whether on drugs or not. Sealfon's and others' research has continued to reveal how brain receptors are involved in hallucinogenic effects; study results are also providing insights into the nature of a mystical or hallucinogenic experience. And so while studies are shedding light on "the brain on hallucinogens," many questions remain. For instance, what causes a "bad trip?"
05-22-2008, 06:26 PM
Where's Timothy Leary when you need him?
He's in space. Literally.